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Znanstvena istraživanja i ispitivanja aktivne sirovine Ichthyol (Sodium Shale Oil Sulfonate) o dokazanom djelovanju i učinkovitom smanjenju simptoma prhuti, crvenila, nadraženosti na koži i vlasištu.

1. Cholcha W., Leuschner J., Leuschner F. Experimental studies on the tolerance of Pale Sulfonated Shale Oil Following Local and Systemic Application. Arnzeim.-Forsch./Drug Res. 44 (II), 2, 1994, 170-177.

2. Warnecke J., Wendt A. Anti-inflammatory action of pale sulfonated shale oil (Ichthyol Pale) in UVB erythema test. Inflamm. Res. 47, 1998, 75-78.

3. Kownatzki, E., Uhrich, S., Schöpf, E., The Effect of a Sulfonated Shale Oil Extract (Ichthyol) on the Migration of Human Neutrophilic Granulocytes in vitro. Arch. Dermatol. Res. 276: 235 - 239, 1984.

4. Gayko, G., Warnecke, J., Volger, C., Zelenkova, H., Antidandruff Efficacy of Sodium Shale Oil Sulfonate Versus Coal Tar, Cosmetics & Toiletries 120 (3), 83 – 92, 2005.

5. Gayko G., Warnecke J., Zelenkova H., The use of the pale type of Ichthyol in cosmetic dermatology. Cosmetic, single-centre, controlled and randomized double blind study for proof of efficacy and tolerance of a combination of Ichthyol Pale 0.5% and synthetic antifungal raw material 0.5% vs 1.0% shampoo in the treatment of moderate to severe dandruff. Clinical dermatology 8 (4):243-247, 2006.

6. Gayko, G., Dealing with dandruff needs integrated approach. Personal Care Magazine, May 2009.

7. Schewe C., Schewe T., Rohde E., Diezel W., Czarnetzki B.M. Inhibitory Effects of sulfonated shale oils (ammonium bituminosulphonates, Ichthyols) on enzymes of polyenoic fatty acid metabolism. Arch. Dermatol. Res. 286: 137-141, 1994.

8. Rabe K.F., Perkins R.S., Dent G., Gustmann H., Barnes P.J. Inhibitory Effects of Sulfonated Shale Oil Fractions on the Oxidative Burst and Ca++ Mobilization in Stimulated Macrophages. Arzneim. Forsch./Drug. Res. 44 (I), 2, 166-170, 1994.

9. Gloor M., Dressel M, Schnyder U.W. The Effect of Coal Tar Distillate, Ichthyol Sodium and Omadine MDS on the Epidermis of the Guinea Pig. Dermatologica 156: 238-243, 1978.

10. Gayko, G.: Sulfonate d'huile de schiste sodique contre les pellicules – Sodium Shale Oil Sulfonate against dandruff, Parfums Cosmétiques Actualités, No.170, Avril/mai 2003.

11. Reinhard, S. and Warnecke, J., Helles sulfoniertes Schieferöl zur lokalen Behandlung der Acne vulgaris, Der Allgemeinarzt 17, (1995) 182 (engl. translation available).

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